In chapter 2 of Baldur's Gate 3, you'll have to brave the shadow curse. As a manifestation of Sharran magic, the curse saps the life of everything caught in its darkness. One act two side quest revolves around lifting the curse from the shadowed lands.
Baldur's Gate 3: How To Remove The Shadow Curse
To remove the Shadow Curse in chapter 2, you'll need to help Halsin with a number of side quests beginning at Last Light Inn in Baldur's Gate 3.